Sister Sa, I saw the melon-eating materials in N groups. It seems that someone has dug up the information of the heroine, saying that the heroine took whitening pills to rejuvenate the whole body, applied facial masks every day, and even In order to delay my aunt's medication, I

Yesterday during the holiday, I did nothing and I was eating melons at home! Two best friends brought their family to my house for dinner, but the men drank and bragged. We women drank coke and melons, which felt much more interesting than their men! What melon do you eat with

? Everyone on earth knows that Li Yifeng has been arrested on PC many times!

Sa Sister I saw the melon-eating materials in N groups. It seems that someone has dug up the information of the heroine, saying that the heroine took whitening pills to rejuvenate the whole body, and applied facial masks and body lotion every day lip mask for Li Yifeng. , even took medicine to delay my aunt's mother, and even took it until she had breastfeeding!

As a professional melon eater, I think it is necessary to tell you what is this medicine that can delay menstruation and may also cause "milk growth"?

Sa Jie guessed that it should be long-acting contraceptive pill .

. Sister Sa has talked a lot about oral compound short-acting contraceptive pills before, but everyone seems to have taken less long-acting people and don’t know much about it. Let’s talk about this knowledge today by eating melons. Let’s talk.

The so-called "long-acting" contraceptive pill is definitely not taken every day like oral short-acting contraceptive pills. Its advantage is that it does not require daily use, and can achieve reliable contraceptive effects, but its side effects are also present, as we will talk about below.

For example, levonorgestrel ethinyl ether tablets , is such an oral long-acting contraceptive pill. It contains ethinylestrother (ethinylestradiol cyclopentyl ether) component, which is a long-acting estrogen. After oral administration, it is absorbed through the gastrointestinal tract and stored in adipose tissue. It slowly releases ethinylestrother , which is inhibited by The lower part of the thalamus-pituitary-ovarian axis is used to inhibit ovarian ovulation and achieve long-term contraceptive effect.

levonorgestrel is a progesterone, which can work together with estrogen to inhibit ovulation, and can also transform endometrium , showing a secretion phenomenon, leading to retract bleeding and forming periodic changes. Take the medicine once a month, and the contraceptive rate can reach 98% or more .

levonorgestrel ethinyl ether tablets are usually taken once on the day of my aunt's arrival, taking the medicine once on the 5th day, taking it for a second time between 20 days, or taking it on the 5th day and 10th day of menstruation. 1 tablet, and the second dose will be taken every month according to the date of the second dose.

Why does this medicine cause milk growth?

is very simple, because there is progesterone , the body will think that you are pregnant. When you think you are pregnant, you may not only experience chest bloating, feel your chest getting bigger, but you may also have nausea, vomiting and other early pregnancy reactions.

also has subcutaneous implants and marquila . The former is common with etogesterone implants, while the latter is common with levonorgesterone sustained release or etogesterone sustained release IUD. Both of these are: It is a progesterone. If you use it, you may not have menstruation, but you may also have breastfeeding and feel that your breasts are getting bigger.

In addition to these, there is another one that you may not have heard of, or have heard of less, that is, long-acting contraceptive injection for medroster acetate , which is also a simple progesterone contraceptive pill. One injection will work for three months.

There are currently two dosage forms of this long-acting contraceptive injection, one is intramuscular injection, with a dose of 150mg/1mL; the other is subcutaneous injection, with a dose of 4mg/0.65mL. Because the microcrystalline solubility at the injection site is low, the pharmacological activity level of is sustainable and remains effective for several months, both dosage forms can be injected once every 3 months (13 weeks).

intramuscular injection dosage form – After a single intramuscular injection, the blood drug level continues to rise for about 3 weeks, reaching the peak blood drug concentration (up to 7ng/mL), and lasting for several days.

Then the blood drug concentration gradually decreased and could not be measured 120-200 days after injection, but the blood drug concentration difference between individuals was large. When the concentration is below 0.1ng/mL, the ovaries will resume ovulation.

subcutaneous injection dosage form – Compared with conventional intramuscular injection, the subcutaneous injection dosage form provides slower and longer-lasting progesterone absorption.

So the dose of progesterone injected subcutaneously can be reduced by 30% (104 mg vs 150 mg) compared with the conventional, the peak blood drug concentration is reduced by half, while the efficacy duration remains unchanged. Although

looks good, there is an issue with this medicine, which is that there may be delays in the recovery of fertility of .

Although the use of long-acting medprogesterone acetate contraceptives will not have a permanent impact on endocrine function, fertility recovery may be delayed.

In women who have stopped taking the pregnancy, 50% will successfully conceive within 10 months after the last injection. But a small number of women's fertility does not return to normal until 18 months after the last injection.

Research believes that after discontinuing the long-acting methylhydroprogesterone acetate contraceptive injection, the duration of ovulation inhibition has nothing to do with the duration of use, but it is related to the weight of women ; after discontinuing, women with lighter weight will conceive faster.

Therefore, before starting to use this injection, the doctor should inform the applicable person that the time of contraception may be extended. If you originally planned to have a child within the next 1 or 2 years, other contraceptive measures are recommended.

Why do people use these things relatively fewer?

Long-acting contraceptive pills are more common than oral short-acting contraceptive pills. After all, its mechanism of action often requires the drug's sustained-release , irregular bleeding, nausea, vomiting, chest bloating, and menstrual disorders. Although adverse reactions such as may sound relatively simple, they can also be very troublesome when they really come to people.

Moreover, for simple progesterone, such as skin or intrauterine sustained release IUD, there is no menstruation after use, and the progesterone-induced fatness and acne acne , it is also some women who decide to give up on them. reason.

Then why are these methods not eliminated?

After all, not everyone is suitable for contraceptive methods containing estrogen. Sister Sa has said before that some people do not recommend using estrogen contraceptive methods, and progesterone-like contraceptive drugs or burying, or even for injection contraceptives. Injection is another option for women who cannot or are unwilling to use estrogen for contraception.

In fact, the most important thing about contraceptive methods is that is suitable for . Some methods seem backward, but for those who are suitable for it, it is better.

chapter says this, but I don’t agree with this fallacy:

pc is a pc, it doesn’t have to be washed, don’t talk about anything, do business to make money, and be equipped with various equipment to improve skills. Even for the sake of turnover, after all, they may want to attract a repeat customer, and live a normal life like us, can it be the same?

Anyway, after seeing this sentence, I smiled:

Finally, for Sister Sa, I stayed up late until 1 o'clock to write this article. I was bitten by a mosquito and helped you to scientifically solve the doubts of growing milk. Please We must help Sister Sa arrange " to watch " and " like "!

References:

[1]Mishell DR Jr. Pharmacokinetics of deposit medroxyprogesterone acetate contraception. J Reprod Med 1996; 41:381.

[2]Ortiz A, Hirol M, Stanczyk FZ, et al. Serum medroxyprogesterone acetate (MPA) concentrations and ovarian function Following intramuscular injection of depo-MPA. J Clin Endocrinol Metab 1977; 44:32.

[3]DEPO-PROVERA- medroxyprogesterone acetate injection. http://labeling.pfizer.com/ShowLabeling.aspx?id=522 (Accessed on July 11, 2014).

#Li Yifeng#